Brugada-syndroom: verschil tussen versies

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1.664 bytes toegevoegd ,  29 nov 2007
Regel 15: Regel 15:
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==Symptomen==
==Electrocardiographic criteria==
Three ECG repolarization patterns in the right precordial leads are recognized in the diagnosis of Brugada syndrome.


Blackouts (collaps), hartkloppingen en plotselinge hartdood. Een belangrijk 'symptoom' is de aanwezigheid van plotseling en jong overleden familieleden (net zoals bij Lange QT syndroom of bv catecholaminerge polymorfe VT (CPVT))
'''Type I''' is the only ECG criterium that is diagnostic of Brugada syndrome. Type I repolarization is characterized by a coved ST-segment elevation >=2 mm (0.2 mV) followed by a negative T wave (see figure). Brugada syndrome is definitively diagnosed when a type 1 ST-segment elevation is observed in >1 right precordial lead (V1 to V3) in the presence or absence of a sodium channel–blocking agent, and in conjunction with one of the following:
*documented ventricular fibrillation (VF)
*polymorphic ventricular tachycardia (VT)
*a family history of sudden cardiac death at <45 years old
*coved-type ECGs in family members
*inducibility of VT with programmed electrical stimulation
*syncope
*nocturnal agonal respiration.


Electrocardiograms of Brugada patients can change over time from type I to type II ECGs and back.
A type III ECG is rather common and is concidered a normal variant.
{| class="wikitable" font-size="90%"
|- style="text-align:center;background-color:#6EB4EB;"
|+'''ST segment abnormalities in the different types of Brugada syndrome'''<cite>Wilde2</cite>
|-
!
!Type I
!Type II
!Type III
|-
!J wave amplitude
|>= 2mm
|>= 2mm
|>= 2mm
|-
!T wave
|negative
|positive or biphasis
|positive
|-
!ST-T configuration
|coved type
|saddleback
|saddleback
|-
!ST segment (terminal portion)
|gradually descending
|elevated >= 1mm
|elevated < 1mm
|-
|}
<gallery caption="Examples of Brugada syndrome type I">
Image:Brugada_syndrome_type1_example1.png
Image:Brugada_syndrome_type1_example2.png
Image:Brugada_syndrome_type1_example3.png
Image:Brugada_syndrome_type1_example4.png
Image:Brugada_syndrome_type1_example5.png
</gallery>
<gallery caption="Examples of Brugada syndrome type II">
Image:Brugada_syndrome_type2_example1.png
</gallery>


==Diagnose en behandeling==
==Diagnose en behandeling==
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